Transient cerebral arteriopathy in childhood2006/07/10 17:25:51

Major clinicoradiological patterns underlying childhood arteriopathic brain infarcts (Lancet 368:8-10,2006 Sebire G)

<Transient cerebral arteriopathy>

Causes

Inflammatory/infectious: varicella zoster virus, other agents (eg, enterovirus, borrelia, bartonella)?

Intracranial dissection: traumatic, inflammatory-infectious?

Spasm, toxic (eg, cocaine)?

Adjuvant thrombotic factors?

Some rare progressive arteriopathies have same presentation as transient cerebral arteriopathy

<Extracranial dissection>

Causes

Traumatic: accidental—direct, stretching, sometimes subtle trauma (non-progressive arteriopathy); non-accidental head injury—shaken baby syndrome (progressive or non-progressive arteriopathies)

Collagen diseases +/− trauma (progressive arteriopathy)

<Moyamoya syndrome>

Causes

Progressive or non-progressive arteriopathies: genetic—sickle-cell disease, neurofibromatosis type 1; toxic—radiotherapy (especially in neurofibromatosis type 1 context); inflammatory/infectious—varicella zoster virus

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